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Professor Dionysios Douroumis

Professor Dionysios Douroumis PGCert, PhD

Professor Dionysios Douroumis

Professor Dionysios Douroumis
PGCert, PhD

Professor in Pharmaceutical Technology and Process Engineering; Director of the Centre for Innovation in Process Engineering and Research (CIPER)

Department of Pharmaceutical, Chemical & Environmental Sciences

Faculty of Engineering & Science

Professor Dennis Douroumis obtained his BSc in Chemistry and PhD from the Department of Pharmacy at Patras University in Greece. He worked as a postdoctoral fellow (2004) at the Friedrich–Schiller University of Jena, Department of Pharmacy for the development of parenteral formulations of antiepileptic drugs (Novartis Pharma, Basel). He also worked as a team leader (2005) in the development of nano-liposomal formulations and treatment of rheumatoid arthritis by applying photodynamic therapy (Biolitec Pharma GmbH.) Following this, he worked for Phoqus Pharmaceutical plc as a senior scientist at the product development department.

His research area focuses on the development of secondary continuous manufacturing by using hot melt extrusion (HME) of extrusion granulation coupled with PAT tools. His group is also involved in development of targeted anticancer drug delivery systems such as SLNs or NLCs produced by high-pressure homogenization. Finally he is actively involved in ink jetting and 3D printing technologies for the development of medical devices (e.g. microneedles, stents) and personalized medicines.

He has published more than 80 research articles, 7 book chapters and edited two books on HME and the delivery of water insoluble APIs. He has patented two proprietary technologies on the coating of transdermal microneedles and printing of drug eluting stents. Professor Douroumis has delivered keynote presentations at national and international conferences while his group presented several poster presentations.

Course participation

  • Drug Design and Delivery
  • Pharmaceutical Product Development, Manufacture and Control

Research group

  • Dr Nikolaos Scoutaris (Research Associate)
  • Dr Mary Malamatary (Research Associate)
  • Steven Ross
  • Tumpa Dey
  • Md Sadeque Mithu
  • Jaya Chakraborty
  • Parastou Emami
  • Chris Pissinato
  • Syed Haque

Previous Members

  • Dr Mohammed Maniruzamann
  • Dr Katarzina Migalska
  • Dr Olga Labovitiadi
  • Dr Ichioma Onyesom
  • Dr Md Jasim Uddin
  • Dr Kapil Kumar Vithani
  • Dr Hiren Moradiya
  • Dr Tariq Islam
  • Dr Mushfiq Akanda
  • Alberto Azor Lafarga

Memberships of editorial boards and associations

  • Editor in "Advances in Pharmaceutical Technology", Wiley, UK
  • Journal of Nanomedicine and Nanotechnology
  • Pharmaceutica Analytica Acta
  • Pharmaceutical Regulatory Affairs
  • E-Journal of Chemistry
  • International Journal of Nano Studies & Technology
  • The Higher Education Academy (UK)
  • Greek Chemists Association (Greece).

Continuous manufacturing via hot melt extrusion (HME)

Medical devices

Nanotechnology

  • Development of novel drug delivery systems for cancer imaging and treatment (liposomes, solid lipid nanoparticles, mesoporous silica nanoparticles and conjugated quantum dots).

Consultancy

CIPER undertakes a range of consultancy projects including preformulation, pharmaceutical/nutraceutical feasibility projects and physicochemical characterization

Other

Patents

Method of coating microneedle devices (WO/20110915 ) - 2011.

Funded research projects

  • Innovative MulticOmponent Drug dEsign (IMODE) for enhancing regional strategic advantages in pharmaceutical and biomedical applications. INTERREG IVA "2 Mers Seas Zeeen", 2016, (€880,891)
  • Development of hot melt extruded water insoluble drugs by using co-processed excipients (Fuji Chemicals, Japan, £60,000)
  • Advanced materials and Pharmaceutical Technologies (AMPTEC), INTERREG IVA "2 Mers Seas Zeeen", 2013, (€104,000)
  • Development of a multifunctional stent. (MultiDES). A European project in collaboration with Universities of Lille 1 and Lille 2 (France) funded by INTERREG IVA "2 Mers Seas Zeeen", 2010, (€892,000)

, , , , and () . International Journal of Pharmaceutics. Elsevier B.V.. pp. 496-505. ISSN 0378-5173 ISSN 0378-5173

, , , , and () . Drug Development and Industrial Pharmacy. Taylor & Francis. pp. 947-957. ISSN 0363-9045 ISSN 0363-9045

, , , , , and () . Journal of Pharmacy and Pharmacology. Wiley. pp. 890-900. ISSN 0022-3573 ISSN 0022-3573

, , , , , , , , and () . Molecular Pharmaceutics. American Chemical Society. pp. 125-133. ISSN 1543-8384 ISSN 1543-8384

, , and () . RSC Advances. Royal Society of Chemistry. pp. 84936-84936.

, , , , and () . International Journal of Pharmaceutics Special Issue on "Continuous Manufacturing and Process Analytical Tools”. Elsevier. pp. 42-51. ISSN 0378-5173 ISSN 0378-5173

, , , , , , , and () . International Journal of Pharmaceutics Special Issue on "Continuous Manufacturing and Process Analytical Tools”. Elsevier B.V.. ISSN 0378-5173 ISSN 0378-5173

, , , , , , , and () . European Journal of Pharmaceutics and Biopharmaceutics. Elsevier. pp. 106-116. ISSN 0939-6411 ISSN 0939-6411

, , , , , and () . International Journal of Pharmaceutics. Elsevier. pp. 161-171. ISSN 0378-5173 ISSN 0378-5173

, and () . International Journal of Pharmaceutics. Elsevier B.V.. pp. 619-622. ISSN 0378-5173 ISSN 0378-5173

, , and () . Molecular Pharmaceutics. ACS Publications. pp. 1040-1049. ISSN 1543-8384 ISSN 1543-8384

, , , , and () . International Journal of Pharmaceutics. Elsevier B.V.. pp. 593-602. ISSN 0378-5173 ISSN 0378-5173

and () . Journal of Pharmacy and Pharmacology. John Wiley & Sons, Inc.. pp. 43-55. ISSN 0022-3573 ISSN 0022-3573

and () . Journal of Pharmacy and Pharmacology. John Wiley & Sons, Inc.. pp. 43-55. ISSN 0022-573 ISSN 0022-573

, , and () . RSC Advances: An international journal to further the chemical sciences. Royal Society of Chemistry. pp. 74212-74219.

, , , , and () . Pharmaceutical Development and Technology. Informa Plc. pp. 531-538. ISSN 1083-7450 ISSN 1083-7450

, , , , , , and () . Journal of Pharmaceutical Sciences. John Wiley & Sons, Inc.. pp. 1819-1828. ISSN 0022-3549 ISSN 0022-3549

, , , and () . Drug Delivery and Translational Research. Springer US. pp. 377-387. ISSN 2190-393X ISSN 2190-393X

, , , , , and () . CrystEngComm. Royal Society of Chemistry. pp. 3573-3583. ISSN 1466-8033 ISSN 1466-8033

, , , , , and () . Crystal Growth & Design. American Chemical Society. pp. 189-198. ISSN 1528-7483 ISSN 1528-7483

, , , and () . Journal of Pharmacy and Pharmacology. John Wiley & Sons, Inc.. pp. 323-337. ISSN 0022-3573 ISSN 0022-3573

, , , , , and () . Molecular Pharmaceutics. American Chemical Society. pp. 4281-4293. ISSN 1543-8384 ISSN 1543-8384

, , , and () . Drug Development and Industrial Pharmacy. Taylor & Francis. pp. 145-156. ISSN 0363-9045 ISSN 0363-9045

, , , , and () . Journal of Chemical & Engineering Data. American Chemical Society. pp. 1861-1866. ISSN 0021-9568 ISSN 0021-9568

, , , , , , and () . Colloids and Surfaces B: Biointerfaces. Elsevier B.V.. pp. 403-410. ISSN 0927-7765 ISSN 0927-7765

, , , and () . Drug Development and Industrial Pharmacy. Informa Plc. pp. 218-227. ISSN 0363-9045 ISSN 0363-9045

, , , and () . Journal of Colloid Science and Biotechnology. American Scientific Publishers. pp. 34-39. ISSN 2164-9634 ISSN 2164-9634

, , , , and () . International Journal of Pharmaceutics. Elsevier B.V.. pp. 199-208. ISSN 0378-5173 ISSN 0378-5173

, and () . Colloids and Surfaces B: Biointerfaces. Elsevier B.V.. pp. 102-108. ISSN 0927-7765 ISSN 0927-7765

, , , and () . Colloids and Surfaces B: Biointerfaces. Elsevier. pp. 8-15. ISSN 0927-7765 ISSN 0927-7765

, , and () . ISRN Pharmaceutics. Hindawi Publishing Corporation. pp. 1-9. ISSN 2090-6145 ISSN 2090-6145

, , , , and () . European Journal of Pharmaceutics and Biopharmaceutics. Elsevier B.V.. pp. 433-442. ISSN 0939-6411 ISSN 0939-6411

, , , , and () . Journal of Nanomedicine and Nanotechnology. OMICS Publishing Group. ISSN 2157-7439 ISSN 2157-7439

, , , , , and () . International Journal of Pharmaceutics. Elsevier. pp. 85-94. ISSN 0378-5173 ISSN 0378-5173

, , , , , , , , and () . Journal of Materials Chemistry. RSC Publishing. pp. 7789-7794. ISSN 0959-9428 ISSN 0959-9428

, , , and () . Colloids and Surfaces B: Biointerfaces. Elsevier B.V.. pp. 275-284. ISSN 0927-7765 ISSN 0927-7765

, and () . AAPS PharmSci Tech. Springer New York. pp. 141-151. ISSN 1530-9932 (Online) ISSN 1530-9932 (Online)

() . Expert Opinion on Drug Delivery. Informa Healthcare. pp. 665-675. ISSN 1742-5247 ISSN 1742-5247

, , , , and () . AAPS PharmSci Tech. Springer New York. pp. 862-871. ISSN 1530-9932 (Online) ISSN 1530-9932 (Online)

, , , , , and () . Journal of Microencapsulation. Informa plc. pp. 74-81. ISSN 0265-2048 ISSN 0265-2048

, , , , , and () . Journal of Biomedical Nanotechnology. American Scientific Publishers. pp. 634-640. ISSN 1550-7033 ISSN 1550-7033

, , and () . Critical Reviews in Biotechnology. Informa plc. pp. 283-301. ISSN 0738-8551 ISSN 0738-8551

, and () . Journal of Pharmacy and Pharmacology. In: Journal of Pharmacy and Pharmacology. John Wiley and Sons, Inc.. pp. 1463-1464. ISSN 2042-7158 ISSN 2042-7158

Browse our research at GALA

and () . In: Hot-Melt Extrusion: Pharmaceutical Applications. John Wiley & Sons, Ltd., Chichester, UK. pp. 177-200. ISBN 978-0-470-71118-7 (hbk), 978-1-1183-0787-8 (ebk)

, , and () . In: Silica Nanoparticles: Preparation, Properties and Uses. Nova Science Publishers, Hauppauge, NY, USA. pp. 81-114. ISBN 978-1-61324-452-4

and () . In: Biomaterials and Nanostructures for Active Implants. Springer, London, UK. pp. 87-125. ISBN 9783642180651

Browse our research at GALA

, , and (Eds.) (2015) . Wiley-Blackwell. ISBN 978-1118573990

and (Eds.) (2013) . Wiley. ISBN 9780470711972

(Ed.) (2012) . John Wiley & Sons, Ltd., Chichester, UK. ISBN 9780470711187

Browse our research at GALA

, and () . In: AAPS Journal. American Association of Pharmaceutical Sciences, Arlington, VA, USA. pp. T3273-T3273. ISSN 1550-7416 (on-line) ISSN 1550-7416 (on-line)

Browse our research at GALA