Genetics and Microbiology

Module summary

Module code: GENE1005
Level: 5
Credits: 15
School: Engineering and Science
Department: Science
Module Coordinator(s):

Specification

Pre and co requisites

Level 4

Aims


• To provide a deeper understanding of the fundamental principles of transmission genetics and molecular genetics, with particular
emphasis on eukaryotic systems.
• To provide students with the ability to analyse and interpret a wide variety of genetic data, such as the outcome of crosses and
data from molecular genetic techniques.
• To examine the growth requirements of micro-organisms, the regulation of biochemical pathways and their ecology, and industrial
applications.
• To examine concepts of microbial pathogenicity and interaction with the human immune system in health and disease.

Learning outcomes

On completion of this course students will be able to:

1. Interpret a variety of types of genetic data, identifying key characteristics of inheritance.
2. Illustrate the benefits of different molecular techniques.
3. Utilize online genomic resources to investigate the sequence and function of a gene and the genomic context in which it exists.
4. Compare and contrast different model organisms used in genetic studies.
5. Survey the human genome categorizing the different types of information it contains and the different methods used to generate the data.
6. Discuss the principles and regulation of gene expression.
7. Recognise the diversity of microbial life and its ecological significance
8. Explain the growth requirements and metabolic regulation exercised by prokaryotes and the means used to control them
9. Discuss the interactions between humans and micro-organisms, including pathogenesis and immunological control

Indicative content

Mendelian genetics and transmission genetics beyond Mendel, Linkage and mapping, Solving genetic problems, Population genetics, The human genome, Gene expression, Molecular techniques, Model organisms, Ethics, Bioinformatic tools and genomic investigations, Performing genetic crosses, An introduction to cytogenetics.
Microbial structure, function, growth, metabolism requirements and ecology. Hazard analysis, sterilisation and disinfection. Pathogenicity of bacteria and immunological responses. Microbiology of the gastrointestinal system and mucosal immunity. Antimicrobial agents.

Assessment

Coursework- 25%
Problem solving assignment, a series of genetic problems and questions to solve/answer
LO - 1-3

Coursework- 25% Essay
1500 words
LO - 3,5

Seen Exam - 50%
LO - ALL
A seen timed assessment. This will either be a seen paper with unseen questions relating to it or 3/4 seen questions with 1 question answered in the assessment

Overall Pass mark 40%