Intermediate Chemistry

Module summary

Module code: CHEM1038
Level: 5
Credits: 30
School: Engineering and Science
Department: Science
Module Coordinator(s): Nichola Coleman

Specification

Pre and co requisites

Successful completion of Level 4 Chemistry.

Aims

This module is designed to supplement material delivered in the Further Inorganic Chemistry, Further Organic Chemistry and Analytical Techniques modules. It aims to provide the opportunity to acquire knowledge of the occurrence, structure, reactivity and importance of selected natural products, to introduce the synthesis and uses of organometallic compounds, to introduce the concept of the symmetry of a molecule and to lay a foundation for its application for structure analysis.

Learning outcomes

On successful completion of this module a student will be able to:
1. Recognise the principal types of compound which are classified as primary and secondary metabolites, and demonstrate knowledge of the structures, occurrences, reactivities and importance of selected groups of natural products
2. Demonstrate knowledge of the application of infrared, electronic and nmr spectroscopies, and mass spectrometry to structure elucidation.
3. Appreciate the fundamental properties of metal-carbon bonds, their preparation, uses and industrial significance
4. Demonstrate an understanding of the symmetry of a molecule and the application of symmetry character tables to vibrational spectroscopy and bonding

Indicative content

Topic 1 Symmetry: Elements and operations, molecular point groups, character tables, application to spectroscopy and bonding.

Topic 2 Interpretive Spectroscopy: Application of infrared spectroscopy, mass spectra, electronic and nmr spectroscopies to structure elucidation.

Topic 3 Organometallic Chemistry: Organometallic compounds of Groups I, II, III and IV. Methods of preparation, structure and bonding. Applications in organic synthesis and industry. Organotransition metal compounds, homogeneous and heterogeneous catalysis.

Topic 4 Natural Products: A suitable selection from:
Carbohydrates: classification, structures, reactions and functions.
Amino acids, peptides and proteins: outline of structures, sequencing and synthetic methods. Isoprenoids, steroids and carotenoids: classification, structures, reactions and biosynthesis. Acetogenins: diversity, classification, structure determination and biosynthesis. Nucleic acids: structures and functions.
Alkaloids: classification and structures, biosynthesis and structure determination.