Pathophysiology of Disease

Module summary

Module code: ANAT1003
Level: 6
Credits: 15
School: Engineering and Science
Department: Science
Module Coordinator(s): Samer El-Daher



• To provide an in-depth approach to explaining mechanisms of human disease;
• To provide an overview of appropriate techniques used to evaluate selected disease processes;
• To develop a critical and analytical approach to explaining specific case histories of human disease.

Learning outcomes

On successful completion of this module a student will be able to:
1. Discuss the mechanisms and changes associated with a range of diseases
2. Critically evaluate the use of clinical findings, imaging techniques, tests of physiological function and laboratory data in the identification, aetiology, diagnosis and pathogenesis of selected disease processes in human tissues and organs;
3. Demonstrate a critical and analytical approach to specific case histories of human disease;
4. Discuss the consequences of changes in morphology and physiology in selected disease states.

Indicative content

• Pathophysiology of enteric infections.
• Gastro-intestinal disease.
• Cardiovascular disease, atherosclerosis, myocardial infarction, conduction disorders.
• Acute and chronic pancreatitis.
• Correlation of cytopathology and histology.
• Haemotopathology.
• Hepatitis, cirrhosis and hepatomas.
• Respiratory disease; restrictive and obstructive disorders, asthma, pneumonia and respiratory distress syndrome. Cystic fibrosis.
• Neoplastic disease.
• Renal disease; classification and laboratory evaluation.
• Viral and bacterial meningitis.
• Parkinson's disease.
• Cerebrovascular accidents.
• Case study evaluations on a range of disorders, both guided and as self-study exercises.

Teaching and learning activity

Learning and teaching activities will include weekly timetabled lectures, tutorials and workshops to enable students to analyse and understand case studies used in the module.


Essay: 50% weighting, 40% pass mark.
Learning Outcomes: 1, 2, 3, 4.
Word Length: 1500 words.
Outline Details: An essay / report on a topic discussed in the lectures.

Report: 50% weighting, 40% pass mark.
Learning Outcomes: 1, 2, 3, 4.
Word length: 1500 words.
Outline Details: A case study analysis written as a report.

Formative Assessment: Workshops to help students acquire problem solving skills and guide through writing and presenting reports relating to the case studies and topics discussed.