Cell Biology and Immunity

Module summary

Module code: BIOL1050
Level: 5
Credits: 15
School: Engineering and Science
Department: Science
Module Coordinator(s): Simon Richardson

Specification

Aims

1. To develop a greater understanding of the regulation of the cell cycle and cell death
2. Explore the differentiation and arrangement of cells in the context organ formation.
3. Explore the internal organisation of the cells.
4. To develop a greater understanding of cell biology of immune function.

Learning outcomes

On successful completion of this module a student will be able to:
1. Discuss the biological processes involved throughout the life of a cell, including cell differentiation, membrane trafficking, motility,
adhesion and communication and cell death
2. Evaluate the molecular and cellular aspects of stem cell biology
3. Describe the features of adaptive and innate immunity and the interplay of cells during an immune response, including biochemical, molecular and cellular aspects.
4. Employ key techniques in the investigation of cell biology.

Indicative content

Cellular and molecular mechanisms of development, cell cycle and differentiation, membrane structure and transport, membrane trafficking and protein sorting, cytoskeletal dynamics, endocytic and secretory pathways, autophagy, cell adhesion and migration, cell communication, stem cell biology, organisation of the nucleus and nuclear transport, innate and adaptive immunity, cell and tissues of the immune system, biochemical regulation of immunity, signal transduction, protein degradation and antigen presentation, molecular aspects in the immune system, examples of autoimmune disease.

Teaching and learning activity

This module will consist mainly of lectures/tutorials, explaining basic concepts. Students will carry out exercises in tutorial sessions that will extend and develop the learning that occurs in lectures. Practical work will include laboratory experiments and observation via microscopy of developmental slides.

Assessment

Laboratory Practical: 50% weighting, 40% pass mark.
Learning Outcome: 4.
Word Length: 1500 words.
Outline Details: Formal practical write up.

Test: 50% weighting, 40% pass mark.
Learning Outcomes: 1 - 3.
Duration: 1.5 hours.
Outline Details: MCQ.

Formative Assessment: The Laboratory write-up is discussed in a lab session prior to the final submission. Feedback re MCQs will be delivered using a practice set of MCQs delivered during a tutorial session.