Advanced Topics in Molecular Biology

Module summary

Module code: GENE0002
Level: 6
Credits: 15
School: Engineering and Science
Department: Science
Module Coordinator(s): Giulia Getti

Specification

Aims

• Build upon students’ prior knowledge of molecular biology by examining advanced topics in the field.
• Provide more detailed understanding of how molecular biology research is carried out and used in the fields of biological research and forensic science.

Learning outcomes

On successful completion of this module a student will be able to:
1. Discuss the inheritance and molecular biology of a variety of human disorders;
2. Critically evaluate the human genome project and the use of the data it generated;
3. Evaluate techniques used in molecular biology investigations including transcriptomics and proteomics;
4. Comment on the current state of gene therapy and the use of transgenic organisms to investigate human disease.

Indicative content

Inheritance of disease moving on from classical transmission genetics to epigenetics, the human genome and use of the data generated by the human genome, gene expression, a variety of techniques used in molecular biology such as the generation of transgenic animals, transcriptomics, proteomics. The manipulation of organisms at the molecular level such as gene therapy and the manipulation of molecular biology processes such as therapeutic antibodies. The use of molecular biology knowledge and techniques in forensic science for instance familial DNA matches and DNA barcoding.