Module summary

Module code: PHAR1020
Level: 5
Credits: 15
School: Engineering and Science
Department: Science
Module Coordinator(s): Michael Leach



To provide a fundamental pharmacological knowledge of the principles of drug action including the concept of drug action at cell, tissue and system levels.

To introduce malfunctions in normal physiology that contribute to pathophysiological conditions and relate mechanisms of drug action to therapeutic intervention of these diseases.

Learning outcomes

On successful completion of this module a student will be able to:
1. Demonstrate a fundamental pharmacological knowledge of the principles of drug action and principles of drug-receptor interactions at receptors, ion channel, enzyme and carrier molecule targets.
2. Be able to relate normal physiological processes to abnormal change and discuss therapeutic use of drugs in various diseases / disorders;
3. Use appropriate IT skills (e.g. on-line search facilities Pubmed, Science Direct) and apply the knowledge derived from scientific journals and other sources in a critical manner
4. Development of problem solving and analytical skills by calculation of pharmacological data.
5. Develop critical analytical skills by analysing scientific data and report writing with appropriate citation and referencing.
6. An understanding of practical pharmacological investigations, practical write up, calculation skills and presentation of pharmacological data.

Indicative content

Principles of drug action; drug targets and non-receptor mechanisms; dose / response relationships, receptor theory, agonists/antagonists. Measurement in pharmacology; principles of bioassay; Schild analysis, receptor binding and Scatchard analysis. Selected topics in pharmacology, selected from for example: drugs from natural products, drugs and the cardiovascular system and autonomic nervous system; drugs and inflammation; drugs and the central nervous system; drugs and the endocrine system. Aspects of toxicity.