Shaobo Zhou

Dr Shaobo Zhou BMed, MMed, PhD, RD, FHEA FIFST

Associate Professor in Nutrition and Health Science

Key details

Dr Shaobo Zhou

Associate Professor in Nutrition and Health Science

Dr Shaobo Zhou is an Associate Professor in Nutrition and Health Science within the Faculty of Engineering and Science and Programme Leader for the BSc Human Nutrition and Health, an accredited course by the Association for Nutrition.

Dr Zhou has gained huge experience in medicine, nutrition education, research and teaching. Trained as a medical doctor for 5 years in Harbin Medical University, then he completed 3 years each on Master (on zinc nutrition) and PhD (on fatty acids on colon cancer) in Chinese National Key Department of Nutrition.

As a qualified MD and nutritionist, Dr Zhou passionately generates, assesses and delivers scientific evidence-based nutritional teaching and advice in a variety of settings to improve health and wellbeing. Dr Zhou has researched zinc nutrition at the National Institute of Nutrition and Food Safety, Chinese Centre for Disease Control and Prevention; studied anti-Parkinson’s diseases at the University of Manchester; applied proteomics to study the nutrients to improve the wound healing and heart disease at the Department of Nutrition in King's College London for 5 years, where his research was awarded by Human Proteomic Organisation; ran a nutritional trial to explore the method for nutrients metabolomics biomarkers in University of Aberystwyth.

As an associate professor, Dr Zhou taught nutrition in Jiamusi Medical University (China) for 4 years; as a Senior Lecturer in Nutrition at the University of Bedfordshire for 14 years, where he developed and led both BSc Food and Nutrition Science (with 91% satisfactory rate in NSS, July 2022) and MSc Food Security in Public Health. His teaching was nominated for: Commitment award, Customer service award, and Governor’s recognition award and his research expanded to use nutrients and nutraceuticals to prevent epilepsy, diabetes, sarcopenia and Alzheimer diseases.

Human nutrition and health Science

Responsibilities within the university

Programme Leader for the BSc Human Nutrition and Health, an accredited course by the Association for Nutrition.

Module participation:

  • Clinical nutrition
  • Advanced human nutrition
  • Nutrition through the lifecycle
  • Project of nutrition

Awards
  • 2016 Scientific research award (4th/9 Authors): Antiepileptic effect and mechanisms of Ganoderma Lucidum Spores in vivo and in vitro studies. Department of Health, Hei Long Jiang Province, PR China
  • 2010 Runner up for three Awards: Commitment Awards, Customer Service Award, Governors Recognition Award respectively in University of Bedfordshire, UK)
  • 2004 Young scientist award: Application of Proteomic technique in collogen synthesis turnover in 3rd annual world congress of Human Proteomics Organisation
  • 1999 Young scientific researcher award, Chinese Ministry of Health, PR China
  • 1999 Young scientific researcher award, Chinese Centre for Disease Control and Prevention, China
  • 1998 Third prize award (1st author), Committee of Science and Technology Progress, Hei Longjiang Province Government, PR China
  • 1998 Presentation award for young researcher, the 4th International Congress on Cancer, Gerontology and Ecology, Beijing, PR China
  • 1997 First prize award (1st author), Educational Committee of Hei Long Jiang Province, PR China
  • 1994 Third prize award (4th author), Committee of Science and Technology Progress, Government of Heilongjiang Province, PR China
  • 1993 Second prize award (4th author), Science and Technology Progress by Educational Committee, Government of Hei Long Jiang Province, PR China
  • 1992 Second prize for teaching,  School of Medicine, Jia Musi University.

Recognition
  • FHEA, Fellow of Higher Education Academy (2010-date)
  • FIFST, Fellow of Institute of Food and Science Technology (2017-date)
  • Registered Dietitian, Chinese Nutrition Society (2017-date)
  • Adjunct Professor, School of Food and Biotechnology, Zhejiang Gongshang University China
  • Visiting Professor of Jiamusi University, China (2009-date)
  • Council Board member of World Federation of Chinese Medicine Societies (2015-2024)
  • External PhD supervisor at Harbin Institute of Technology, P.R. China (2018-2020)
  • Public governor, Luton and Dunstable University Hospital NHS Foundation Trust. UCL teaching hospital (2015-2018)
  • Board member and Vice chair of Luton Healthwatch (2013-2015)
  • Board member of Scrutiny the Health and Social Care Review Group, Luton Council, UK (2014-15)
  • Member of British Nutrition Society, UK (1939092, 2002-date)
  • Member of the British Society for Proteome Research (BSPR 301, 2003-date)
  • Standing committee member of Chinese Life Scientist Society in the UK (2011-2015)
  • Member of Epilepsy Research UK (2015-date)
  • Member of Zinc-UK
  • Member of Zinc-Net Europe
  • External academic advisor for the course accreditation by University of Suffolk in 2018
  • Editor for Special Issue: Biomedical Aspects of Nutrition and Functional Food (2021)
  • Topical Advisory Panel (TAP) in Food Chemistry in Molecules (2021-date)
  • Topical Advisory Panel Member of Molecules (2021)
  • Editorial board member Maternal and Paediatric Nutrition (2015-date)
  • Editorial board member of Paediatrics & Health Research (2016-date)
  • Editorial board member of Food & Nutrition Journal (2016-date)

Reviewer for 30 renowned journals including BMC Pregnancy and Childbirth; Biomed Research International; Biological Trace Element Research; Food and Function; Food Control; Food Research International; Frontiers in Paediatrics; Food Chemistry; Frontiers in Pharmacology, Journal of Cereal Science; Journal of Chromatography B; Journal of Food Biochemistry; Journal of Dairy Science. Journal of Functional Food; Journal of Nutrition; Journal of the Science of Food and Agriculture; Journal of Traditional and Complementary Medicine; International Journal of Biological Macromolecules; Molecular Nutrition and Food Science; Marine drugs; Proteome Science; Phytotherapy research; Pharmaceuticals, Plosone; Polymers; Nutrition and Food Technology.

Research / Scholarly interests

My research focuses on nutrients (e.g. zinc, polysaccharides, and fatty acids) and nutraceuticals (e.g. extracts of milk, Ganoderma Lucidum and marine food) on health (e.g. zinc nutritional status, diabetes, Alzheimer disease, epilepsy, bone health, sarcopenia, cancer). Working to develop and validate zinc biomarkers to assess dietary zinc nutritional status and zinc bioavailability in humans. I have a wide range of interests in the application of cellular/pathology, proteomics and metabolomic techniques to nutrition related diseases. Have been working on biomarker discovery for wound healing and alcohol induced protein profile and on the opioids receptors in Parkinson’s disease as while as dietary biomarker using metabolomics techniques. I have contributed both REF assessment in 2014 and 2021 when I worked in University of Bedfordshire.

Accepting PhD Students

PhD projects

Please email s.zhou@greenwich.ac.uk to discuss PhD opportunities.

Key funded projects

  1. Heilongjiang Provincial Key Laboratory of Microecology-Immune Regulation Network and Related Diseases Chinese Ministry of science and technology, 70,000 CYN, (PI,4.2022-12. 2023)
  2. Ombar chocolate development on health review, European regional developments fund program. £1000, (PI, 2019).
  3. University of Bedfordshire, Rising star research investment fund £5000, (co-PI, 2012)
  4. Co-application and working on a £1 million grant Food standard agency: Biomarker discovery for the assessment of zinc status. £982833 April 2009 (PI Prof. JH. Beattie).
  5. Chinese Nutritional Association, £27000 match fee for a PhD studentship to study zinc biomarker discovery. October 2009.
  6. University of Bedfordshire, £42000 bursary for two Ph.D. studentship. 2009.
  7. University of Bedfordshire, £5000 for research informed teaching.
  8. Chinese National Natural Scientific Foundation: Some biomarker on the assessment of the zinc nutritious status (PI, 1998-2000).
  9. Scientific Research Foundation of Chinese Ministry of Health: Effect of dietary zinc on the metallothionein mRNA expression. (PI, 1998-1999).
  10. Chinese Postdoctoral Scientific Research Foundation: Effect of dietary and physiological conditions on some biomarker of zinc. (PI, 1997-1999).
  11. Hong Da Ltd, Effects of fatty acids composition on chemoprevention in a rat model of colon tumour (to Chen B and Zhou S, 1994-1997).

Recent publications

Article

Chen, Lian , Wang, Dong, Liu, Wei, Zhou, Shaobo , Gu, Qing , Zhou, Tao (2024), Immunomodulation of exopolysaccharide produced by Lacticaseibacillus rhamnosus ZFM216 in cyclophosphamide-induced immunosuppressed mice by modulating gut microbiota. Elsevier. In: , , , . Elsevier, International Journal of Biological Macromolecules, 283: 137619 (Part 2) ISSN: 0141-8130 (Print), 1757-448X (Online) (doi: https://doi.org/10.1016/j.ijbiomac.2024.137619) NB Item availability restricted.

Wang, Xixiang , Guo, Yujie, Li, Pengfei, Ma, Xiaojun , Xu, Jingjing , Liu, Lu , Liu, Yu , Ren, Xiuwen , Wang, Ying , Meng, Liping (2024), Impact of vitamin A on the risk of mild cognitive impairment and Alzheimer’s disease pathology in high-fat-diet–treated APP/PS1 mice. Wiley. In: , , , . Wiley, Food Frontiers 2643-8429 (Online) (doi: https://doi.org/10.1002/fft2.498).

Fan, Ruyan , Wei, Wensong, Wei, Youjing, Lin, Xue , Zhou, Shaobo , Wang, Lu (2024), Phenolics-rich extracts from Agarwood leaf-tea alleviate dextran sulfate sodium (DSS)-induced ulcerative colitis via modulating intestinal barrier function and gut microbiota. Wiley. In: , , , . Wiley, Molecular Nutrition and Food Research ISSN: 1613-4125 (Print), 1613-4133 (Online) (doi: https://doi.org/10.1002/mnfr.202400566) NB Item availability restricted.

Nie, Yinyue , Huang, Luyue, Wang, Luchuan, Zeng, Pei , Gong, Chao , Song, Lin , Guo, Jin , Zhou, Shaobo (2024), Vitamin D3 treatment reduced epileptic neuronal damage by inhibiting apoptosis and increasing vitamin D receptor expression in an in vivo epileptic model. IMR Press. In: , , , . IMR Press, Journal of Integrative Neuroscience ISSN: 0219-6352 (Print), 1757-448X (Online) (doi: ) NB Item availability restricted.

Liu, Yu , Wang, Xixiang, Mu, Jie, Gu, Yiyao , Zhou, Shaobo , Ma, Xiaojun , Xu, Jingjing , Liu, Lu , Ren, Xiuwen , Duan, Zhi (2024), Developing a risk model for early diagnosis of metabolic syndrome in Chinese adults aged 40 years and above based on BMI/HDL-C: a cross-sectional study. BioMed Central. In: , , , . BioMed Central, BMC Endocrine Disorders, 24: 223 1472-6823 (Online) (doi: https://doi.org/10.1186/s12902-024-01752-9).

Gong, Chao , Zeng, Pei, Lian, Beibei, Li, Jiawei , Liu, Jiahao , Liu, Yuanyuan , Fang, Liya , Tian, Huiling , Wang, Luchuan , Jiang, Zhimei (2024), Associations of risk factors and the number of risk factors with the classification, GMFCS level and comorbidities with cerebral palsy: a retrospective study. BioMed Central. In: , , , . BioMed Central, BMC Pediatric 1471-2431 (Online) (doi: ).

Liu, Xiaoze , Zhang, Wen, Chen, Jingwen, Fu, Ruihui , Lin, Xue , Zhou, Shaobo , Wang, LU (2024), Investigating the inhibition of xanthine oxidase by five catechins: kinetic studies, spectroscopy, molecular docking, and dynamics simulations. Elsevier. In: , , , . Elsevier, International Journal of Biological Macromolecules, 281: 136231 (Part 1) ISSN: 0141-8130 (Print), 1879-0003 (Online) (doi: https://doi.org/10.1016/j.ijbiomac.2024.136231) NB Item availability restricted.

Liu, Yu , Wang, Xixiang, Ren, Xiuwen, Zhang, Chi , Zhou, Shaobo , Wang, Ying , Xu, Jingjing , Liu, Lu , Wang, Yueyong , Yuan, Linhong (2024), Association of physical activity and dietary diversity with cognitive function in the elderly with Type 2 diabetes mellitus: findings from a cross-sectional study. Taylor and Francis Online - American Nutrition Association. In: , , , . Taylor and Francis Online - American Nutrition Association, Journal of the American Nutrition Association (JANA) . pp. 1-11 ISSN: 2769-7061 (Print), 2769-707X (Online) (doi: https://doi.org/10.1080/27697061.2024.2401592) NB Item availability restricted.

Ma, Zheng Feei and , Zhou, Shaobo (2024), Physical activity, exercise and mental disorders of older adults. Alpha Psychiatry (AP). In: , , , . Alpha Psychiatry (AP), Alpha Psychiatry 2757-8038 (Online) (doi: ) NB Item availability restricted.

Liu, Lu , Xu, Jingjing, Huang, Xiaochen, Wang, Ying , Ma, Xiaojun , Wang, Xixiang , Liu, Yu , Ren, Xiuwen , Li, Jiahao , Wang, Yueyong (2024), DHA dietary intervention caused different hippocampal lipid and protein profile in ApoE-/- and C57BL/6J mice. Elsevier. In: , , , . Elsevier, Biomedicine & Pharmacotherapy, 177: 117088 ISSN: 0753-3322 (Print), 1950-6007 (Online) (doi: https://doi.org/10.1016/j.biopha.2024.117088).

Ma, Xiaojun , Li, Pengfei, Liu, Yu, Liu, Lu , Xu, Jingjing , Wang, Xixiang , Zhou, Shaobo , Ren, Xiuwen , Wang, Ying , Yuan, Linhong (2024), Suboptimal diet quality is associated with the incidence of type 2 diabetes mellitus in middle-aged and older populations in China: evidence from population-based cross-sectional study. Elsevier. In: , , , . Elsevier, Nutrition Research ISSN: 0271-5317 (Print), (doi: https://doi.org/10.1016/j.nutres.2024.05.008) NB Item availability restricted.

Zhu, YuZhu , Wang, Dong, Zhou, Shaobo, Zhou, Tao (2024), Hypoglycemic effects of Gynura Divaricata (L.) DC Polysaccharide and action mechanisms via modulation of gut microbiota in diabetic mice. American Chemical Society (ACS). In: , , , . American Chemical Society (ACS), Journal of Agricultural and Food Chemistry ISSN: 0021-8561 (Print), 1520-5118 (Online) (doi: https://doi.org/10.1021/acs.jafc.4c00626) NB Item availability restricted.

Zhou, Shaobo , Hu, Xiao, Lin, Lianzhu (2024), Editorial. Food-derived bioactive peptides: preparation, identification, and structure-activity relationship. MDPI. In: , , , . MDPI, Frontier in Nutrition, 11 2296-861X (Online) (doi: https://doi.org/10.3389/fnut.2024.1412875).

Li, He , Guan, Kaifang Guan, Liu, Min, Jiang, Wen , Yan, Fengjuan , Zhu, Aihua , Zhou, Shaobo , Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221116, Jiangsu, China. , School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150090, Heilongjiang, China. , School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning 530008, Guangxi, China. (2024), Identification and anti-oxidative potential of Milk Fat Globule Membrane (MFGM)- derived bioactive peptides released through in vitro gastrointestinal digestion. Elsevier. In: , , , . Elsevier, Bioorganic Chemistry: 107232 (0045-2) ISSN: 0045-2068 (Print), 1090-2120 (Online) (doi: https://doi.org/10.1016/j.bioorg.2024.107232) NB Item availability restricted.

Li, Pengfei , Xu, Jingjing, Guo, Yujie, Ma, Xiaojun , Zhou, Shaobo , Zhang, Chi , Yua, Huiyan , Wangd, Ying , Wanga, Xixiang , Yuan, Linhong (2024), Association of plasma vitamin A level with type 2 diabetes mellitus: a community aging population-based cross-sectional study. Elsevier - Sciopen. In: , , , . Elsevier - Sciopen, Food Science and Human Wellness, 13 . pp. 1-18 ISSN: 2097-0765 (Print), 2213-4530 (Online) (doi: https://doi.org/10.26599/FSHW.2022.9250173) NB Item availability restricted.

Yu, Si-Jia , Hu, Shu-Min, Zhu, Yu-Zhu, Zhou, Shaobo , Dong, Shuai , Zhou, Tao (2023), Pickering emulsions stabilized by soybean protein isolate/chitosan hydrochloride complex and their applications in essential oil delivery. Elsevier. In: , , , . Elsevier, International Journal of Biological Macromolecules, 250: 126146 . pp. 1-12 ISSN: 0141-8130 (Print), (doi: https://doi.org/10.1016/j.ijbiomac.2023.126146).

Gong, Chao , Liu, Annan, Lian, Beibei, Wu, Xixi , Zeng, Pei , Hao, Chaoli , Wang, Bobo , Jiang, Zhimei , Pang, Wei , Guo, Jin (2023), Prevalence and related factors of epilepsy in children and adolescents with cerebral palsy: a systematic review and meta-analysis. Frontiers Media. In: , , , . Frontiers Media, Frontiers in Pediatrics, 11: 1189648 . pp. 1-16 2296-2360 (Online) (doi: https://doi.org/10.3389/fped.2023.1189648).

Dong, Shuai , HU, Shu-Min, Yu, Shaobo, Zhou, Shaobo , Zhou, Tao (2023), Soybean protein isolate/chitosan complex-rutin microcapsules. Elsevier. In: , , , . Elsevier, International Journal of Biological Macromolecules, 243: 125323 . pp. 1-9 ISSN: 0141-8130 (Print), (doi: https://doi.org/10.1016/j.ijbiomac.2023.125323).

Chen, Liang , Qian, Wen-Wen, Zhou, Shaobo, Zhou, Tao , Gu, Qing (2023), Fabrication of whey protein/pectin double layer microcapsules for improving survival of Lacticaseibacillus rhamnosus ZFM231. Elsevier. In: , , , . Elsevier, International Journal of Biological Macromolecules, 242: 125030 (4) ISSN: 0141-8130 (Print), (doi: https://doi.org/10.1016/j.ijbiomac.2023.125030).

Wang, Xixiang , Wang, Ying, Ma, Xiaojun, Zhou, Shaobo , Xu, Jinjing , Guo, Yujie , Liu, Lu , Liu, Yu , Gao, Lifang , Yuan, Linhong (2023), Gender-specific association of SLC19A1 and MTHFR genetic polymorphism with oxidative stress biomarkers and plasma folate levels in older adults. Elsevier. In: , , , . Elsevier, Experimental Gerontology, 178: 112208 ISSN: 0531-5565 (Print), (doi: https://doi.org/10.1016/j.exger.2023.112208).

Wan, Cheng , Jiang, Hui, Tang, Meng-Ting, Zhou, Tao , Zhou, Shaobo (2022), Purification, physico-chemical properties and antioxidant activity of polysaccharides from Sargassum fusiforme by hydrogen peroxide/ascorbic acid-assisted extraction. Elsevier. In: , , , . Elsevier, International Journal of Biological Macromolecules, 223 (Part A) . pp. 490-499 ISSN: 0141-8130 (Print), (doi: https://doi.org/10.1016/j.ijbiomac.2022.11.030).

Xu, Jingjing , Huang, Xiaochen, Guo, Yujie, Ma, Xiaojun , Li, Pengfei , Zhou, Shaobo , Zhang, Chi , Chen, Rui , Van Halm‐Lutterodt, Nicholas , Yuan, Linhong (2022), Discrepant modulating effects of dietary docosahexaenoic acid on cerebral lipids, fatty acid transporter expression and soluble beta‐amyloid levels in ApoE −/− and C57BL/6J mice. Wiley. In: , , , . Wiley, Neuropathology and Applied Neurobiology, 49: e12855 (1) ISSN: 0305-1846 (Print), 1365-2990 (Online) (doi: https://doi.org/10.1111/nan.12855).

Wang, Xixiang , Ma, Xiaojun, Xu, Jingjing, Guo, Yujie , Zhou, Shaobo , Yu, Huiyan , Yuan, Linhong (2022), Association of cluster determinant 36, scavenger receptor class B type 1, and major facilitator superfamily domain containing the 2a genetic polymorphism with serum lipid profile in aging population with type 2 diabetes mellitus. Frontiers Media. In: , , , . Frontiers Media, Frontiers in Nutrition, 9: 981200 . pp. 1-12 2296-861X (Online) (doi: https://doi.org/10.3389/fnut.2022.981200).

Pang, Wei , Lu, Shuqing, Zheng, Rong, Li, Xin , Yang, Shunbo , Feng, Yuxia , Wang, Shuqiu , Guo, Jin , Zhou, Shaobo (2022), Investigation into antiepileptic effect of ganoderic acid A and its mechanism in seizure rats induced by pentylenetetrazole. Hindawi. In: , , , . Hindawi, BioMed Research International, 2022: 5940372 . pp. 1-14 ISSN: 2314-6133 (Print), 2314-6141 (Online) (doi: https://doi.org/10.1155/2022/5940372).

Hu, Xiao , Liu, Jing, Li, Jun, Song, Yuqiong , Chen, Shengjun , Zhou, Shaobo , Yang, Xianqing (2022), Preparation, purification, and identification of novel antioxidant peptides derived from Gracilariopsis lemaneiformis protein hydrolysates. Frontiers Media. In: , , , . Frontiers Media, Frontiers in Nutrition, 9: 971419 . pp. 1-13 2296-861X (Online) (doi: https://doi.org/10.3389/fnut.2022.971419).

Hu, Yu , Shu-Xiang, Wang, Fu-Yu, Wu, Ke-Jia, Wu , Rui-Ping, Shi , Li-Hong, Qin , Chun-Feng, Lu , Shu-Qiu, Wang , Fang-Fang, Wang , Zhou, Shaobo (2022), Effects and mechanism of Ganoderma lucidum polysaccharides in the treatment of diabetic nephropathy in streptozotocin-induced diabetic rats. Hindawi. In: , , , . Hindawi, BioMed Research International, 2022: 4314415 . pp. 1-13 ISSN: 2314-6133 (Print), 2314-6141 (Online) (doi: https://doi.org/10.1155/2022/4314415).

Long, Xiaoshan , Hu, Xiao, Zhou, Shaobo, Huan, Xiang , Shengjun, Chen , Laihao, Li , Shucheng, Liu , Xianqing, Yang (2021), Optimized degradation and inhibition of α-glucosidase activity by Gracilaria lemaneiformis polysaccharide and its production in vitro. MDPI. In: , , , . MDPI, Marine Drugs, 20: 13 (1) . pp. 1-22 1660-3397 (Online) (doi: https://doi.org/10.3390/md20010013).

Hu, Xiao , Zhou, Ya, Zhou, Shaobo, Chen, Shengjun , Wu, Yanyan , Li, Laihao , Yang, Xianqing (2021), Purification and identification of novel xanthine oxidase inhibitory peptides derived from round scad (Decapterus maruadsi) protein hydrolysates. MDPI. In: , , , . MDPI, Marine Drugs, 19: 538 (10) . pp. 1-14 ISSN: 1660-3397 (Print), (doi: https://doi.org/10.3390/md19100538).

Xu, Weili , Lv, Kangxing, Mu, Wei, Zhou, Shaobo , Yang, Yang (2021), Encapsulation of α-tocopherol in whey protein isolate/chitosan particles using oil-in-water emulsion with optimal stability and bioaccessibility. Elsevier. In: , , , . Elsevier, LWT - Food Science and Technology, 148: 111724 ISSN: 0023-6438 (Print), (doi: https://doi.org/10.1016/j.lwt.2021.111724) NB Item availability restricted.

Li, He , Wang, Rongchun, Wang, Lifeng, Li, Lin , Ma, Ying , Zhou, Shaobo (2020), Bovine milk fat globule epidermal growth factor VIII activates PI3K/Akt signaling pathway and attenuates sarcopenia in rat model induced by d-galactose. Elsevier. In: , , , . Elsevier, Food Bioscience, 40: 100847 ISSN: 2212-4292 (Print), 2212-4306 (Online) (doi: https://doi.org/10.1016/j.fbio.2020.100847).

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