Advanced Drug Delivery Platforms

Faculty

At the Medway Centre for Pharmaceutical Sciences, we offer a robust pipeline of innovative drug delivery technologies designed to meet the needs of modern pharmaceutical development. Our expertise spans conventional, modified release, and targeted delivery systems, with analytical depth and translational focus.

We have particular strengths in:

Soft Chewable Formulations

  • Designed for paediatric, geriatric, and dysphagia patients
  • Optimised for taste, disintegration, and swallowability
  • Mechanical texture analysis to evaluate chewability, cohesion, and mechanical strength
  • Suitable for APIs requiring mucosal or buccal absorption

Solid Oral Dosage Forms

  • Development of immediate- and modified-release tablets, capsules, and multiparticulate systems
  • Expertise in granulation, compression, coating, and encapsulation techniques
  • Formulation of fixed-dose combinations and bioenhanced systems
  • In vitro performance testing using USP Apparatus I & II, disintegration, and friability assessments
  • Stability and scale-up support

Liquid Oral Dosage Forms

  • Formulation of solutions, suspensions, syrups, and emulsions for paediatric, geriatric, or dysphagic populations
  • Optimisation of viscosity, taste masking, and dose accuracy
  • Rheological and microbiological testing for quality and palatability
  • Compatibility and preservative efficacy studies
  • Customisable for APIs with solubility or stability challenges

Long-Acting Injectable (LAI) Formulations

  • Formulation of depot and microparticle-based injectables for sustained delivery
  • Use of PLGA, lipid-based, and biodegradable polymers
  • Evaluation of syringeability, release kinetics, and biocompatibility
  • Stability and release studies under accelerated and real-time conditions

Microfluidic Microsphere Engineering

  • Lab-on-chip microfluidics for scalable production of monodisperse particles
  • Customisable particle size, encapsulation efficiency, and controlled-release profiles
  • Application in LAIs, inhalation, and oral delivery systems
  • Ideal for precision delivery in both human and veterinary contexts

Inhalation Drug Delivery Technologies

  • Next Generation Impactor (NGI) for aerodynamic particle size distribution profiling
  • Breathing Simulator for replicating patient-specific inspiratory flow rates
  • Suitable for DPIs and MDIs formulations
  • Analysis of deposition behaviour in lungs and oropharyngeal regions
  • Ideal for formulation development of pulmonary therapeutics and vaccines

Topical and Semi-Solid Formulations

  • Development of creams, gels, hydrogels, films, ointments, and pastes
  • Designed for dermal, mucosal, or transdermal drug delivery
  • Texture profiling for spreadability, tackiness, and sensory performance
  • In vitro release testing using Franz diffusion cells
  • Stability assessment under ICH and accelerated conditions
  • Suitable for local and systemic therapeutic applications

Biological and Microbiological Services

We offer:

  • Mammalian cell culture for bioassay screening
  • Microbial testing and preservative efficacy